Summary

Basic Descriptive Statistics
! Data Leakage
Documentation GitHub
Find the shortcut. Learn the biology.
Automated quality control for genomic machine learning datasets: scores the biases, duplicates and data leakage a classifier could exploit before you train on it.
Searching test set AGO2_eCLIP_Manakov2022_test.csv.gz against train set AGO2_eCLIP_Manakov2022_train.csv.gz
Data Leakage:!WarningHow a flag is decided →
gb-qc v1.0.0 · run 2026-09-15 22:37:28

Basic Descriptive Statistics

Filename AGO2_eCLIP_Manakov2022_test.csv.gz AGO2_eCLIP_Manakov2022_train.csv.gz
Number of sequences 324171 2495535
Minimum length 66 66
Mean length 72.38 72.38
Maximum length 76 78
!

Data Leakage

Every test sequence searched against the train set with MMseqs2, and scored on its best hit. Similarity is min(query coverage, target coverage) × percent identity: how much of the shorter sequence the alignment spans, times how much of that matches. The histogram is the distribution of those best hits.

The flag is the percentage of test sequences at or above the threshold: Pass at 0%, Warning below 2%, Fail at 2% or more. A test sequence that near-duplicates a training one is one the model has already seen, so the accuracy it earns there is not evidence. What to do about it →

The panel under the histogram lists those alignments, up to the first 100; every one of them, listed or not, is exported to mmseqs/mmseqs2_search_result.tsv beside this report. Its columns are:

Query (Q)
Identifier of the test sequence: seq_<i>_test, where i is its 0-based position in the input test file.
Target (T)
Identifier of the train sequence: seq_<i>_train, where i is its 0-based position in the input train file.
Q Cov.
Fraction of the query sequence covered by the alignment (0–1).
T Cov.
Fraction of the target sequence covered by the alignment (0–1).
% Identity
Percent identical aligned positions in the aligned region.
% Similarity
Similarity score used for leakage detection, calculated as min(Q Cov., T Cov.) × % Identity.
E-value
MMseqs2 E-value (lower is more "significant").
Alignment
Click “Show” to expand the alignment visualisation for a row.
Filename AGO2_eCLIP_Manakov2022_test.csv.gz AGO2_eCLIP_Manakov2022_train.csv.gz
Data Leakage (percentage) 0.40% 0.16%
Data Leakage (count) 1287 4020
Similarity Histogram
10323 high-similarity alignments (first 100 shown)
Query (Q) Target (T) Q Cov. T Cov. % Identity % Similarity E-value Alignment
seq_140704_test seq_1028412_train 1.00 1.00 98.6 98.60 3.31e-32
seq_12188_test seq_335778_train 1.00 1.00 98.6 98.60 8.97e-33
seq_141577_test seq_1003407_train 1.00 1.00 98.6 98.60 3.31e-32
seq_22172_test seq_66998_train 1.00 1.00 98.6 98.60 8.97e-33
seq_106050_test seq_837864_train 1.00 1.00 98.6 98.60 3.31e-32
seq_27396_test seq_311176_train 1.00 1.00 98.6 98.60 8.97e-33
seq_285220_test seq_2196831_train 1.00 1.00 98.6 98.60 3.31e-32
seq_158741_test seq_1232377_train 1.00 1.00 98.6 98.60 8.97e-33
seq_287593_test seq_2224635_train 1.00 1.00 98.6 98.60 8.97e-33
seq_16555_test seq_11009_train 1.00 1.00 98.6 98.60 8.97e-33
seq_200925_test seq_1666065_train 1.00 1.00 98.6 98.60 8.97e-33
seq_19518_test seq_115898_train 1.00 1.00 98.6 98.60 8.97e-33
seq_27234_test seq_260903_train 1.00 1.00 98.6 98.60 8.97e-33
seq_30194_test seq_300384_train 1.00 1.00 98.6 98.60 8.97e-33
seq_39771_test seq_304764_train 1.00 1.00 98.6 98.60 8.97e-33
seq_288156_test seq_2224635_train 1.00 1.00 98.6 98.60 8.97e-33
seq_206870_test seq_1656510_train 1.00 1.00 98.6 98.60 8.97e-33
seq_98877_test seq_748903_train 1.00 1.00 98.6 98.60 3.31e-32
seq_23779_test seq_81771_train 1.00 1.00 98.6 98.60 8.97e-33
seq_209453_test seq_1623656_train 1.00 1.00 98.6 98.60 8.97e-33
seq_108958_test seq_760923_train 1.00 1.00 98.6 98.60 3.31e-32
seq_37336_test seq_103787_train 1.00 1.00 98.6 98.60 8.97e-33
seq_14447_test seq_159287_train 1.00 1.00 98.6 98.60 8.97e-33
seq_38482_test seq_19250_train 1.00 1.00 98.6 98.60 8.97e-33
seq_204613_test seq_1658883_train 1.00 1.00 98.6 98.60 8.97e-33
seq_245786_test seq_1903009_train 1.00 1.00 98.6 98.60 3.31e-32
seq_242945_test seq_1888940_train 1.00 1.00 98.6 98.60 3.31e-32
seq_211309_test seq_1573804_train 1.00 1.00 98.6 98.60 8.97e-33
seq_213368_test seq_1657140_train 1.00 1.00 98.6 98.60 8.97e-33
seq_1202_test seq_190456_train 1.00 1.00 98.6 98.60 8.97e-33
seq_8368_test seq_293468_train 1.00 1.00 98.6 98.60 8.97e-33
seq_20372_test seq_251520_train 1.00 1.00 98.6 98.60 8.97e-33
seq_200103_test seq_1576858_train 1.00 1.00 98.6 98.60 8.97e-33
seq_38524_test seq_6275_train 1.00 0.99 98.6 97.22 2.09e-31
seq_106050_test seq_836259_train 0.99 1.00 98.6 97.22 7.71e-31
seq_16377_test seq_233369_train 0.99 1.00 98.6 97.22 2.09e-31
seq_36799_test seq_133811_train 1.00 0.99 98.6 97.22 2.09e-31
seq_215271_test seq_1553920_train 1.00 0.99 98.6 97.22 2.09e-31
seq_213368_test seq_1561830_train 0.99 1.00 98.6 97.22 2.09e-31
seq_199645_test seq_1546319_train 1.00 1.00 97.2 97.20 4.57e-31
seq_22172_test seq_126830_train 1.00 1.00 97.2 97.20 4.57e-31
seq_22172_test seq_23130_train 1.00 1.00 97.2 97.20 4.57e-31
seq_106990_test seq_831941_train 1.00 1.00 97.2 97.20 1.69e-30
seq_216972_test seq_1666358_train 1.00 1.00 97.2 97.20 4.57e-31
seq_216972_test seq_1643095_train 1.00 1.00 97.2 97.20 4.57e-31
seq_27494_test seq_169356_train 1.00 1.00 97.2 97.20 4.57e-31
seq_27494_test seq_88365_train 1.00 1.00 97.2 97.20 4.57e-31
seq_27494_test seq_185404_train 1.00 1.00 97.2 97.20 4.57e-31
seq_29477_test seq_138644_train 1.00 1.00 97.2 97.20 4.57e-31
seq_26191_test seq_11330_train 1.00 1.00 97.2 97.20 4.57e-31
seq_210444_test seq_1630436_train 1.00 1.00 97.2 97.20 4.57e-31
seq_37479_test seq_83939_train 1.00 1.00 97.2 97.20 4.57e-31
seq_37479_test seq_139815_train 1.00 1.00 97.2 97.20 4.57e-31
seq_200177_test seq_1666065_train 1.00 1.00 97.2 97.20 4.57e-31
seq_210105_test seq_1623656_train 1.00 1.00 97.2 97.20 4.57e-31
seq_16555_test seq_258022_train 1.00 1.00 97.2 97.20 4.57e-31
seq_39448_test seq_139591_train 1.00 1.00 97.2 97.20 4.57e-31
seq_35667_test seq_7345_train 1.00 1.00 97.2 97.20 4.57e-31
seq_133624_test seq_1030894_train 1.00 1.00 97.2 97.20 1.69e-30
seq_2885_test seq_139591_train 1.00 1.00 97.2 97.20 4.57e-31
seq_2885_test seq_102653_train 1.00 1.00 97.2 97.20 4.57e-31
seq_217523_test seq_1666453_train 1.00 1.00 97.2 97.20 4.57e-31
seq_206870_test seq_1571645_train 1.00 1.00 97.2 97.20 4.57e-31
seq_36799_test seq_287977_train 1.00 1.00 97.2 97.20 4.57e-31
seq_242819_test seq_1880095_train 1.00 1.00 97.2 97.20 1.69e-30
seq_141090_test seq_1015663_train 1.00 1.00 97.2 97.20 1.69e-30
seq_18243_test seq_32094_train 1.00 1.00 97.2 97.20 4.57e-31
seq_20020_test seq_53927_train 1.00 1.00 97.2 97.20 4.57e-31
seq_45454_test seq_149617_train 1.00 1.00 97.2 97.20 4.57e-31
seq_45454_test seq_17085_train 1.00 1.00 97.2 97.20 4.57e-31
seq_45454_test seq_302655_train 1.00 1.00 97.2 97.20 4.57e-31
seq_202954_test seq_1646799_train 1.00 1.00 97.2 97.20 4.57e-31
seq_4106_test seq_294083_train 1.00 1.00 97.2 97.20 4.57e-31
seq_26040_test seq_141523_train 1.00 1.00 97.2 97.20 4.57e-31
seq_2398_test seq_16443_train 1.00 1.00 97.2 97.20 4.57e-31
seq_26532_test seq_285114_train 1.00 1.00 97.2 97.20 4.57e-31
seq_97035_test seq_757302_train 1.00 1.00 97.2 97.20 1.69e-30
seq_97035_test seq_816506_train 1.00 1.00 97.2 97.20 1.69e-30
seq_14500_test seq_177536_train 1.00 1.00 97.2 97.20 4.57e-31
seq_212869_test seq_1561746_train 1.00 1.00 97.2 97.20 4.57e-31
seq_107953_test seq_748138_train 1.00 1.00 97.2 97.20 1.69e-30
seq_6092_test seq_230097_train 1.00 1.00 97.2 97.20 4.57e-31
seq_20710_test seq_66432_train 1.00 1.00 97.2 97.20 4.57e-31
seq_530_test seq_336042_train 1.00 1.00 97.2 97.20 4.57e-31
seq_132835_test seq_1065633_train 1.00 1.00 97.2 97.20 1.69e-30
seq_215686_test seq_1671970_train 1.00 1.00 97.2 97.20 4.57e-31
seq_30862_test seq_253250_train 1.00 1.00 97.2 97.20 4.57e-31
seq_16033_test seq_205135_train 1.00 1.00 97.2 97.20 4.57e-31
seq_16033_test seq_174906_train 1.00 1.00 97.2 97.20 4.57e-31
seq_211309_test seq_1648224_train 1.00 1.00 97.2 97.20 4.57e-31
seq_32812_test seq_58742_train 1.00 1.00 97.2 97.20 4.57e-31
seq_19252_test seq_138520_train 1.00 1.00 97.2 97.20 4.57e-31
seq_14449_test seq_134198_train 1.00 1.00 97.2 97.20 4.57e-31
seq_45368_test seq_106396_train 1.00 1.00 97.2 97.20 4.57e-31
seq_8050_test seq_17183_train 1.00 1.00 97.2 97.20 4.57e-31
seq_14143_test seq_47412_train 1.00 1.00 97.2 97.20 4.57e-31
seq_14143_test seq_57625_train 1.00 1.00 97.2 97.20 4.57e-31
seq_14143_test seq_103610_train 1.00 1.00 97.2 97.20 4.57e-31
seq_14143_test seq_93663_train 1.00 1.00 97.2 97.20 4.57e-31
seq_32296_test seq_197182_train 1.00 1.00 97.2 97.20 4.57e-31